منابع مشابه
The regulation of intracellular pH in the diabetic myocardium.
In myocardial cells, as in any given cell, steady-state Ž . intracellular pH pH is strictly maintained within a nari Ž row range at relatively alkaline values. Resting pH 7.1– i . 7.2 is determined by the algebraic sum of acid-loading and acid-extruding processes. Whenever acid-loading exceeds acid extrusion, pH falls. The degree to which pH i i changes is inversely related to the intracellular...
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incorrectly interpreted to be irreversible if only stress-reinjection images were acquired. Dr. Freedman's finding of low differential uptake in 11% of their patients after reinjection appears to confirm our results. We agree with Dr. Freedman that similar information might be obtained if an analysis of thallium activity after a resting injection of 20`T1 were used. Preliminary data in our labo...
متن کاملMulti-dose crystalloid cardioplegia preserves intracellular sodium homeostasis in myocardium.
The goal of this study was to assess the effect of multi-dose St Thomas' cardioplegia on intracellular sodium homeostasis in a rat heart model. A new magnetic resonance method was applied which enable us to detect intracellular Na changes without chemical shift reagents. Three groups of isolated rat hearts were subjected to 51 min of ischemia and 51 min of reperfusion at 37 degrees C: Group 1-t...
متن کاملIntracellular manganese ions provide strong T1 relaxation in rat myocardium.
The efficacy of manganese ions (Mn2+) as intracellular (ic) contrast agents was assessed in rat myocardium. T1 and T2 and Mn content were measured in ventricular tissue excised from isolated perfused hearts in which a 5-min wash-in with 0, 30, 100, 300, or 1000 microM of Mn dipyridoxyl diphosphate (MnDPDP) was followed by a 15-min wash-out to remove extracellular (ec) Mn2+. An inversion recover...
متن کاملRegulation of respiration in myocardium in the transient and steady state.
1H/31P NMR has followed the metabolic response to increased work in the glucose- and pyruvate-perfused rat myocardium during a heart cycle and at the steady state. With electrical pacing and dobutamine, the heart O2 consumption increases by 56%. The phosphocreatine (PCr) level initially declines, but recovers within 15 min to its control level; the oxymyoglobin (MbO2) saturation decreases by 15...
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ژورنال
عنوان ژورنال: Japanese Circulation Journal
سال: 1969
ISSN: 0047-1828,1347-4839
DOI: 10.1253/jcj.32.1821